Four Zn(II) complexes containing a pyridyl triazine core (L1 3-(2-pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5ââ?¬Â²,5ââ?¬Â³-disulfonic acid\ndisodium salt and L2 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine-4ââ?¬Â²,4ââ?¬Â³-disulfonic acid sodium salt) were synthesized, and their\nchemical formulas were finalized as [Zn(L1)Cl2]Ã?·5H2OÃ?·ZnCl2 (1), [Zn(L1)2Cl2]Ã?·4H2OÃ?·2CH3OH (2), [Zn(L2)Cl2]Ã?·3H2OÃ?·CH3OH\n(3), and [Zn(L2)2Cl2] (4). The synthesized complexes are water soluble, making them good candidates for biological applications.\nAll four complexes have been characterized by elemental analysis and 1H NMR, IR, and UV-Vis spectroscopy. The IR stretching\nfrequency of NN and CN bonds of complexes 1ââ?¬â??4 have shifted to lower frequencies in comparison with free ligands, and\na bathochromic shift was observed in UV-Vis spectra of all four complexes. The binding studies of ligands and complexes 1ââ?¬â??4 with\nbovine serum albumin (BSA) resulted binding constants (Kb) of 3.09 Ã?â??104MâË?â??1, 12.30 Ã?â??104MâË?â??1, and 16.84 Ã?â??104MâË?â??1 for ferene,\ncomplex 1, and complex 2, respectively, indicating potent serum distribution via albumins.
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